0001193125-10-180398 Sample Contracts

FIRST AMENDMENT TO THE AMENDED AND RESTATED COLLABORATION LICENSE AGREEMENT BETWEEN OSI PHARMACEUTICALS, INC. AND AVEO PHARMACEUTICALS, INC.

Collaboration License Agreement • August 6th, 2010 • Aveo Pharmaceuticals Inc • Pharmaceutical preparations

• Contract Type
  Collaboration License Agreement
• Filed
  August 6th, 2010
• Company
  Aveo Pharmaceuticals Inc
• Industry
  Pharmaceutical preparations

This First Amendment (the “Amendment”) effective as of the last date set forth on the signature page hereof, by and between OSI Pharmaceuticals, Inc. (“OSI”) and AVEO Pharmaceuticals, Inc. (“AVEO”) amends the Amended and Restated Collaboration License Agreement between OSI and AVEO, dated July 16, 2009 (the “Agreement”).