0001193125-10-257487 Sample Contracts

SIXTH AMENDMENT DATED SEPTEMBER 29, 2010
Trius Therapeutics Inc • November 12th, 2010 • Pharmaceutical preparations

Nancy Ridge Technology Center, L.P., a California limited partnership (“Lessor”), and Trius Therapeutics, Inc., a Delaware corporation, (“Lessee”), hereby amend the Lease dated September 7, 2004 for Suites #101, 104, 105 & 106 at 6310 Nancy Ridge Drive, San Diego, CA 92121 (“Premises”):

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