0001193125-11-059249 Sample Contracts

INDEMNIFICATION AGREEMENT
Indemnification Agreement • March 8th, 2011 • Curis Inc • Biological products, (no disgnostic substances) • Delaware

This Agreement is made as of the day of 20 , by and between Curis, Inc., a Delaware corporation (the “Corporation”), and (the “Indemnitee”), a director of the Corporation.

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FOURTH AMENDMENT TO OFFER LETTER
Offer Letter • March 8th, 2011 • Curis Inc • Biological products, (no disgnostic substances)

This Fourth Amendment (the “Amendment”), effective as of December 10, 2010 (the “Effective Date”), to the offer letter dated May 2, 2001, as amended by the amendments to the offer letter dated May 10, 2002, December 14, 2006 and October 27, 2008 (the “Offer Letter”) is entered into by and between Curis, Inc., a Delaware corporation (the “Company”), and Changgeng Qian, M.D., Ph.D. (the “Executive”).

THIRD AMENDMENT TO OFFER LETTER
Offer Letter • March 8th, 2011 • Curis Inc • Biological products, (no disgnostic substances)

This Third Amendment (the “Amendment”), effective as of December 10, 2010 (the “Effective Date”), to the offer letter dated December 10, 2003, as amended by the amendments to the offer letter dated October 31, 2006 and October 27, 2008 (the “Offer Letter”) is entered into by and between Curis, Inc., a Delaware corporation (the “Company”), and Michael P. Gray (the “Executive”).

THIRD AMENDMENT TO OFFER LETTER
Offer Letter • March 8th, 2011 • Curis Inc • Biological products, (no disgnostic substances)

This Third Amendment (the “Amendment”), effective as of December 10, 2010 (the “Effective Date”), to the offer letter dated January 11, 2001, as amended by the amendments to the offer letter dated October 31, 2006 and October 27, 2008 (the “Offer Letter”) is entered into by and between Curis, Inc., a Delaware corporation (the “Company”), and Mark W. Noel (the “Executive”).

SECOND AMENDMENT TO OFFER LETTER
Offer Letter • March 8th, 2011 • Curis Inc • Biological products, (no disgnostic substances)

This Second Amendment (the “Amendment”), effective as of December 10, 2010 (the “Effective Date”), to the offer letter dated March 21, 2008, as amended by the amendment to the offer letter dated June 3, 2010 (the “Offer Letter”) is entered into by and between Curis, Inc., a Delaware corporation (the “Company”), and Dr. Mitchell Keegan (the “Executive”).

SECOND AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • March 8th, 2011 • Curis Inc • Biological products, (no disgnostic substances)

This Second Amendment (the “Amendment”), effective as of December 10, 2010 (the “Effective Date”), to the employment agreement, dated as of September 18, 2007, as amended by the amendment to the employment agreement dated October 27, 2008 (the “Employment Agreement”) is entered into by and between Curis, Inc., a Delaware corporation (the “Company”), and Daniel R. Passeri (the “Executive”).

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