0001193125-11-076920 Sample Contracts

AMENDMENT TO AGREEMENT AND PLAN OF MERGER

Agreement and Plan of Merger • March 25th, 2011 • Ampio Pharmaceuticals, Inc. • Pharmaceutical preparations • Colorado

• Contract Type
  Agreement and Plan of Merger
• Filed
  March 25th, 2011
• Company
  Ampio Pharmaceuticals, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Colorado

This Amendment, dated as of March 22, 2011 (this “Amendment”), to the Agreement and Plan of Merger, dated as of September 3, 2010 (the “Merger Agreement”), by and among DMI BioSciences, Inc., a Colorado corporation (the “Company”), Ampio Pharmaceuticals, Inc., a Delaware corporation (“Parent”), Ampio Acquisition, Inc., a Colorado corporation and wholly-owned subsidiary of Parent (the “Merger Subsidiary”); and the Company’s Control Shareholders.