0001193125-11-271872 Sample Contracts

SECOND SUPPLEMENTAL INDENTURE
Second Supplemental Indenture • October 14th, 2011 • Wood Park Properties LLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

SECOND SUPPLEMENTAL INDENTURE (this “Second Supplemental Indenture”), dated as of August 16, 2011, among American Medical Systems, Inc., a Delaware corporation (“AMS”), and Laserscope, a California corporation (“Laserscope,” and, together with AMS, the “Successor Guarantors”), each a wholly-owned subsidiary of Endo Pharmaceuticals Holdings Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

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FIRST SUPPLEMENTAL INDENTURE
Supplemental Indenture • October 14th, 2011 • Wood Park Properties LLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of June 17, 2011, among American Medical Systems Holdings, Inc., a Delaware corporation, American Medical Systems, Inc., a Delaware corporation, AMS Research Corporation, a Delaware corporation, AMS Sales Corporation, a Delaware corporation, and Laserscope, a California corporation (collectively, the “Guaranteeing Subsidiaries”), each a subsidiary of Endo Pharmaceuticals Holdings Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

THIRD SUPPLEMENTAL INDENTURE
Third Supplemental Indenture • October 14th, 2011 • Wood Park Properties LLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

THIRD SUPPLEMENTAL INDENTURE (this “Third Supplemental Indenture”), dated as of September 26, 2011, among Generics Bidco II, LLC, a Delaware limited liability company, Generics International (US Holdco), Inc., a Delaware corporation, Generics International (US Midco), Inc., a Delaware corporation, Generics International (US Parent), Inc., a Delaware corporation, Moores Mill Properties L.L.C., a Delaware limited liability company, Quartz Specialty Pharmaceuticals, LLC, a Delaware limited liability company, and Wood Park Properties LLC, a Delaware limited liability company (collectively, the “Guaranteeing Subsidiaries”), each a subsidiary of Endo Pharmaceuticals Holdings Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

SUPPLEMENTAL INDENTURE
Supplemental Indenture • October 14th, 2011 • Wood Park Properties LLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of December 13, 2010, among Penwest Pharmaceuticals Co. (“Penwest”), a Washington corporation and a subsidiary of Endo Pharmaceuticals Holdings Inc. (or its permitted successor), a Delaware corporation (the “Company”), and Generics International (US), Inc., a Delaware corporation and a subsidiary of the Company (together with Penwest, the “Guaranteeing Subsidiaries,” and each, a “Guaranteeing Subsidiary”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

SIXTH SUPPLEMENTAL INDENTURE
Sixth Supplemental Indenture • October 14th, 2011 • Wood Park Properties LLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

SIXTH SUPPLEMENTAL INDENTURE (this “Sixth Supplemental Indenture”), dated as of August 16, 2011, among American Medical Systems, Inc., a Delaware corporation (“AMS”), and Laserscope, a California corporation (“Laserscope,” and, together with AMS, the “Successor Guarantors”), each a wholly-owned subsidiary of Endo Pharmaceuticals Holdings Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

THIRD SUPPLEMENTAL INDENTURE
Supplemental Indenture • October 14th, 2011 • Wood Park Properties LLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

THIRD SUPPLEMENTAL INDENTURE (this “Third Supplemental Indenture”), dated as of February 17, 2011, among Ledgemont Royalty Sub LLC (the “Guaranteeing Subsidiary”), a Delaware limited liability company and a subsidiary of Endo Pharmaceuticals Holdings Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

SEVENTH SUPPLEMENTAL INDENTURE
Seventh Supplemental Indenture • October 14th, 2011 • Wood Park Properties LLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

SEVENTH SUPPLEMENTAL INDENTURE (this “Seventh Supplemental Indenture”), dated as of September 26, 2011, among Generics Bidco II, LLC, a Delaware limited liability company, Generics International (US Holdco), Inc., a Delaware corporation, Generics International (US Midco), Inc., a Delaware corporation, Generics International (US Parent), Inc., a Delaware corporation, Moores Mill Properties L.L.C., a Delaware limited liability company, Quartz Specialty Pharmaceuticals, LLC, a Delaware limited liability company, and Wood Park Properties LLC, a Delaware limited liability company (collectively, the “Guaranteeing Subsidiaries”), each a subsidiary of Endo Pharmaceuticals Holdings Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

FOURTH SUPPLEMENTAL INDENTURE
Fourth Supplemental Indenture • October 14th, 2011 • Wood Park Properties LLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

FOURTH SUPPLEMENTAL INDENTURE (this “Fourth Supplemental Indenture”), dated as of April 5, 2011, among Vintage Pharmaceuticals, LLC (the “Guaranteeing Subsidiary”), a Delaware limited liability company and a subsidiary of Endo Pharmaceuticals Holdings Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

SECOND SUPPLEMENTAL INDENTURE
Second Supplemental Indenture • October 14th, 2011 • Wood Park Properties LLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

SECOND SUPPLEMENTAL INDENTURE (this “Second Supplemental Indenture”), dated as of December 21, 2010, among Generics Bidco I, LLC (the “Guaranteeing Subsidiary”), a Delaware limited liability company and a subsidiary of Endo Pharmaceuticals Holdings Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

FIFTH SUPPLEMENTAL INDENTURE
Supplemental Indenture • October 14th, 2011 • Wood Park Properties LLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

FIFTH SUPPLEMENTAL INDENTURE (this “Fifth Supplemental Indenture”), dated as of June 22, 2011, among American Medical Systems Holdings, Inc., a Delaware corporation, American Medical Systems, Inc., a Delaware corporation, AMS Research Corporation, a Delaware corporation, AMS Sales Corporation, a Delaware corporation, and Laserscope, a California corporation (collectively, the “Guaranteeing Subsidiaries”), each a subsidiary of Endo Pharmaceuticals Holdings Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

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