0001193125-11-300047 Sample Contracts

COMMERCIALIZATION AGREEMENT
Commercialization Agreement • November 7th, 2011 • Santarus Inc • Pharmaceutical preparations • California

This COMMERCIALIZATION AGREEMENT (this “Agreement”) is made as of August 22, 2011 (the “Effective Date”), by and between Depomed, Inc., a California corporation (“Depomed”), and Santarus, Inc., a Delaware corporation (“Santarus”). Each of Depomed and Santarus is referred to herein individually as a “party” and collectively as the “parties.”

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AMENDMENT NO. 4 TO OTC LICENSE AGREEMENT
Otc License Agreement • November 7th, 2011 • Santarus Inc • Pharmaceutical preparations

This Amendment No. 4 (the “Amendment”) to the OTC License Agreement dated October 17, 2006, as amended (the “License”), between MSD Consumer Care, Inc. (formerly known as Schering-Plough Healthcare Products, Inc.) (“MCC”) and Santarus, Inc. (“Santarus”) is made as of the last date of signature below (the “Effective Date”).

FIRST AMENDMENT TO SUBLEASE (Suite 106)
Sublease • November 7th, 2011 • Santarus Inc • Pharmaceutical preparations

THIS FIRST AMENDMENT TO SUBLEASE (this “First Amendment”) is entered into and effective as of the 5th day of August, 2011, by and between Avnet, Inc., a New York corporation with its principal offices at 2211 South 47th Street, Phoenix, AZ 85034 (“Sublessor”), and Santarus, Inc., a Delaware corporation, with its principal offices at 3721 Valley Centre Drive, Suite 400, San Diego, CA 92130 (“Sublessee”).

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