0001193125-12-153621 Sample Contracts

EIGHTH SUPPLEMENTAL INDENTURE
Supplemental Indenture • April 6th, 2012 • Express Scripts Inc • Retail-drug stores and proprietary stores • New York

The Eighth Supplemental Indenture (this “Eighth Supplemental Indenture”), dated as of April 2, 2012, among Express Scripts Holding Company (formerly Aristotle Holding, Inc.), a corporation duly organized and existing under the laws of the State of Delaware (the “Company”), the Guarantors listed as signatories hereto (each, an “Existing Guarantor” and collectively, the “Existing Guarantors”), Medco Health Solutions, Inc., a Delaware corporation, and its subsidiaries listed as signatories hereto (each, an “Additional Guarantor,” and, collectively, the “Additional Guarantors”) and Wells Fargo Bank, National Association, as trustee under the indenture referred to below (the “Trustee”).

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