0001193125-12-365315 Sample Contracts

THERMO FISHER SCIENTIFIC INC. as Issuer AND THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., as Trustee FIFTH SUPPLEMENTAL INDENTURE Dated as of August 22, 2012 $500,000,000 of 1.850% Senior Notes due 2018 and $800,000,000 of 3.150% Senior Notes due 2023
Fifth Supplemental Indenture • August 22nd, 2012 • Thermo Fisher Scientific Inc. • Measuring & controlling devices, nec • New York

THIS FIFTH SUPPLEMENTAL INDENTURE (the “Fifth Supplemental Indenture”) is dated as of August 22, 2012 between THERMO FISHER SCIENTIFIC INC., a Delaware corporation (the “Company”) and THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., a national banking association (the “Trustee”).

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