0001193125-12-379341 Sample Contracts

FIRST AMENDMENT TO SHAREHOLDER RIGHTS AGREEMENT
Shareholder Rights Agreement • September 4th, 2012 • Cell Therapeutics Inc • Pharmaceutical preparations • Washington

This FIRST AMENDMENT TO SHAREHOLDER RIGHTS AGREEMENT is made and entered into as of August 31, 2012 (this “Amendment”), to be effective as of September 2, 2012, between Cell Therapeutics, Inc., a Washington corporation (the “Company”), and Computershare Trust Company, N.A., a federally chartered trust company (the “Rights Agent”). The capitalized terms used and not otherwise defined herein have the respective meanings given to them in that certain Shareholder Rights Agreement, between the Company and Rights Agent, dated as of December 28, 2009 (the “Rights Agreement”).

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