0001193125-12-470970 Sample Contracts

THIS WARRANT AND THE SHARES OF COMMON STOCK ISSUED UPON ITS EXERCISE ARE SUBJECT TO THE RESTRICTIONS ON TRANSFER SET FORTH IN SECTION 5 OF THIS WARRANT AND ARTICLE 6 OF THE PURCHASE AGREEMENT
Common Stock Purchase Warrant • November 14th, 2012 • Idera Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • Delaware

This Warrant is one in a series of warrants (the “Series Warrant”) issued pursuant to that certain Convertible Preferred Stock and Warrant Purchase Agreement, dated November 9, 2012, among the Company, the Registered Holder and the other parties thereto (the “Purchase Agreement”).

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IDERA PHARMACEUTICALS, INC. REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • November 14th, 2012 • Idera Pharmaceuticals, Inc. • Biological products, (no disgnostic substances)

REGISTRATION RIGHTS AGREEMENT (this “AGREEMENT”), dated as of November 9, 2012, by and among IDERA PHARMACEUTICALS, INC., a corporation organized under the laws of the State of Delaware (the “COMPANY”), and each of the persons or entities listed on Exhibit A hereto (the “PURCHASERS”).

IDERA PHARMACEUTICALS, INC. CONVERTIBLE PREFERRED STOCK AND WARRANT PURCHASE AGREEMENT November 9, 2012
Convertible Preferred Stock and Warrant Purchase Agreement • November 14th, 2012 • Idera Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • Delaware

This Convertible Preferred Stock and Warrant Purchase Agreement (this “AGREEMENT”) is entered into as of the date set forth above by and among Idera Pharmaceuticals, Inc., a Delaware corporation (the “COMPANY”), and the undersigned purchasers (each a “PURCHASER” and collectively, the “PURCHASERS”) set forth on the Schedule of Purchasers attached hereto as Exhibit A (the “SCHEDULE OF PURCHASERS”). The parties hereby agree as follows:

IDERA PHARMACEUTICALS, INC. AMENDMENT NO. 1 TO COMMON STOCK PURCHASE WARRANT
Common Stock Purchase Warrant • November 14th, 2012 • Idera Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • Delaware

This Amendment No. 1 to Common Stock Purchase Warrant (this “Agreement”) is made as of November 9, 2012, by and between Idera Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and Pillar Pharmaceuticals I, L.P. (the “Registered Holder”).

IDERA PHARMACEUTICALS, INC. AMENDMENT NO. 1 TO CONVERTIBLE PREFERRED STOCK AND WARRANT PURCHASE AGREEMENT
Convertible Preferred Stock and Warrant Purchase Agreement • November 14th, 2012 • Idera Pharmaceuticals, Inc. • Biological products, (no disgnostic substances) • Delaware

This Amendment No. 1 to Convertible Preferred Stock and Warrant Purchase Agreement (this “Agreement”) is made as of November 9, 2012, by and between Idera Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and Pillar Pharmaceuticals I, L.P. (the “Purchaser”).

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