0001193125-12-519146 Sample Contracts

OPTION CANCELLATION AGREEMENT
Option Cancellation Agreement • December 31st, 2012 • Insite Vision Inc • Pharmaceutical preparations

This letter relates to the nonqualified stock option to acquire 2,844,374 shares of InSite Vision Incorporated (“Company”) common stock granted to you on December 1, 2010 (“2010 Option”) pursuant to the Notice of Grant of Stock Option and Terms and Conditions of Stock Option executed by you and the Company on December 9, 2010 (“Grant Notice”).

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