FOURTH AMENDMENT TO LEASELease • February 19th, 2013 • Regulus Therapeutics Inc. • Pharmaceutical preparations
This letter concerns certain Lease dated as of March 19, 2010, as amended by that certain First Amendment to Lease dated as of April 26, 2010, that certain Second Amendment to Lease dated as of January 26, 2011, that certain Third Amendment to Lease dated as of February 27, 2012 and that certain Fourth Amendment to Lease dated as of November 19, 2012 (the “Fourth Amendment” and collectively, as the same may have been further amended, amended and restated, supplemented or modified from time to time, the “Lease”), between BMR-3545-3575 John Hopkins LP (“Landlord”) and Regulus Therapeutics Inc. (“Tenant”). Capitalized terms not otherwise defined herein shall have the meanings given them in the Lease.
