0001193125-13-107407 Sample Contracts

AMENDMENT No. 2 to LICENSE AND DISTRIBUTION AGREEMENT
License and Distribution Agreement • March 14th, 2013 • Cornerstone Therapeutics Inc • Pharmaceutical preparations

This AMENDMENT No. 2 to the LICENSE AND DISTRIBUTION AGREEMENT executed between CHIESI FARMACEUTICI S.p.A. and CORNERSTONE THERAPEUTICS INC. Dated May 6, 2009 (the “License”) is made and effective this 1st day of December, 2012 and provides as follows:

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FIRST AMENDMENT TO THE LICENSE AND DISTRIBUTION AGREEMENT between CHIESI FARMACEUTICI S.p.A. and CORNERSTONE THERAPEUTICS INC. September 28, 2010
License and Distribution Agreement • March 14th, 2013 • Cornerstone Therapeutics Inc • Pharmaceutical preparations

This FIRST AMENDMENT (this “First Amendment”) is made as of this 28th day of September, 2010 between Chiesi Farmaceutici S.p.A. a company incorporated under the laws of Italy, with its principal place of business at Via Palermo 26/A, 43122 Parma, Italy (“Chiesi”) and Cornerstone Therapeutics, Inc. a company incorporated under the laws of Delaware, with its principal place of business at 1255 Crescent Green Drive, Suite 250, Cary, North Carolina 27518, USA (“Cornerstone”, and together with Chiesi, the “Parties”, each a “Party”).

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