0001193125-13-321939 Sample Contracts

THIRD AMENDMENT TO AMENDED AND RESTATED SERVICES AND SUPPLY AGREEMENT
Services and Supply Agreement • August 6th, 2013 • Santarus Inc • Pharmaceutical preparations • California

This THIRD AMENDMENT (this “Amendment”) is dated as of June 4, 2013 (the “Effective Date”), is entered into among Biogen Idec MA Inc. (“Biogen Idec”), Covella Pharmaceuticals, Inc. (a wholly owned subsidiary of Santarus, “Covella”) and Santarus, Inc. (“Santarus”) (hereinafter collectively, the “Parties”).

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Second Amendment to License Agreement among Pharming Group N.V., Pharming Intellectual Property B.V. and Santarus, Inc.
License Agreement • August 6th, 2013 • Santarus Inc • Pharmaceutical preparations

This Second Amendment (the “Second Amendment”) to the License Agreement dated September 10, 2010, as amended on June 18, 2012 (the “License”), among Pharming Group N.V. on behalf of itself and each of its Affiliates, including Pharming Intellectual Property B.V. and Pharming Technologies B.V. (“Pharming”) and Santarus, Inc. (“Santarus”) is made as of May 1, 2013 (the “Second Amendment Effective Date”).

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