0001193125-13-322359 Sample Contracts

OREXIGEN THERAPEUTICS, INC. AMENDMENT NO. 1 TO SECOND AMENDED AND RESTATED EMPLOYMENT AGREEMENT FEBRUARY 15, 2013
Employment Agreement • August 7th, 2013 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations • California

This Amendment No. 1 is intended to modify the SECOND AMENDED AND RESTATED EMPLOYMENT AGREEMENT (the “Agreement”) dated June 14, 2011 by and between OREXIGEN THERAPEUTICS, INC. (“Orexigen” or the “Company”) with its principal place of business located at 3344 N. Torrey Pines Ct., Suite 200, La Jolla, CA 92037 and MICHAEL A. NARACHI (“Executive”). All capitalized terms used herein and not otherwise defined shall have the meanings assigned to such terms in the Agreement.

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OREXIGEN THERAPEUTICS, INC. AMENDMENT NO. 1 TO AMENDED AND RESTATED EMPLOYMENT AGREEMENT FEBRUARY 15, 2013
Employment Agreement • August 7th, 2013 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations • California

This Amendment No. 1 is intended to modify the AMENDED AND RESTATED EMPLOYMENT AGREEMENT (the “Agreement”) dated February 22, 2010 by and between OREXIGEN THERAPEUTICS, INC. (“Orexigen” or the “Company”) with its principal place of business located at 3344 N. Torrey Pines Ct., Suite 200, La Jolla, CA 92037 and [ ] (“Executive”). All capitalized terms used herein and not otherwise defined shall have the meanings assigned to such terms in the Agreement.

OREXIGEN THERAPEUTICS, INC. AMENDMENT NO. 4 TO AMENDED AND RESTATED EMPLOYMENT AGREEMENT FEBRUARY 15, 2013
Employment Agreement • August 7th, 2013 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations • California

Reference is made to the AMENDED AND RESTATED EMPLOYMENT AGREEMENT (the “Agreement”) dated February 22, 2010 by and between OREXIGEN THERAPEUTICS, INC. (“Orexigen” or the “Company”) with its principal place of business located at 3344 N. Torrey Pines Ct., Suite 200, La Jolla, CA 92037 and MARK BOOTH (“Executive”), AMENDMENT NO. 1 TO THE AMENDED AND RESTATED EMPLOYMENT AGREEMENT dated June 14, 2011 (the “First Amendment”), AMENDMENT NO. 2 TO THE AMENDED AND RESTATED EMPLOYMENT AGREEMENT dated November 1, 2011 (the “Second Amendment”), and AMENDMENT NO. 3 TO THE AMENDED AND RESTATED EMPLOYMENT AGREEMENT dated March 15, 2012 (the “Third Amendment”). All capitalized terms used herein and not otherwise defined shall have the meanings assigned to such terms in the Agreement.

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