0001193125-13-360785 Sample Contracts

—] Shares OPHTHOTECH CORPORATION COMMON STOCK, $0.001 PAR VALUE PER SHARE UNDERWRITING AGREEMENT
Underwriting Agreement • September 9th, 2013 • Ophthotech Corp. • Pharmaceutical preparations • New York
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Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. LICENSE, MANUFACTURING AND SUPPLY AGREEMENT
License, Manufacturing and Supply Agreement • September 9th, 2013 • Ophthotech Corp. • Pharmaceutical preparations • California

PRODUCT, and NEKTAR AL agrees to undertake the manufacture and supply of the REAGENT specified under this AGREEMENT in accordance with the terms and conditions specified under this AGREEMENT.

SECOND AMENDED AND RESTATED EMPLOYMENT AGREEMENT
Employment Agreement • September 9th, 2013 • Ophthotech Corp. • Pharmaceutical preparations • New York

This Second Amended and Restated Employment Agreement (the “Agreement”) is made and entered into this August 27th, 2013 (the “Effective Date”), by and between Ophthotech Corporation (“Company”), and Samir Patel, M.D. (“Executive”).

OPHTHOTECH CORPORATION Incentive Stock Option Agreement Granted Under 2013 Stock Incentive Plan
Incentive Stock Option Agreement • September 9th, 2013 • Ophthotech Corp. • Pharmaceutical preparations
OPHTHOTECH CORPORATION Nonstatutory Stock Option Agreement Granted Under 2013 Stock Incentive Plan
Nonstatutory Stock Option Agreement • September 9th, 2013 • Ophthotech Corp. • Pharmaceutical preparations
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