0001193125-13-402729 Sample Contracts

] Shares RELYPSA, INC. COMMON STOCK, $0.001 PAR VALUE PER SHARE UNDERWRITING AGREEMENT
Underwriting Agreement • October 17th, 2013 • Relypsa Inc • Pharmaceutical preparations • New York
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AMENDED AND RESTATED INTELLECTUAL PROPERTY LICENSE AND ASSIGNMENT AGREEMENT
Intellectual Property License and Assignment Agreement • October 17th, 2013 • Relypsa Inc • Pharmaceutical preparations • California

This Amended and Restated Intellectual Property License and Assignment Agreement (this “ Restated Agreement”) dated as of November 23, 2009 (the “Amendment Date”) is entered into by and between Relypsa, Inc., a Delaware corporation, having a place of business at 5301 Patrick Henry Drive, Santa Clara, CA 95054 (“Relypsa”) and Ilypsa, Inc., a Delaware corporation and a wholly-owned subsidiary of Amgen Inc., having a place of business at One Amgen Center Drive, Thousand Oaks, CA 91320 (“Ilypsa”).

AMENDMENT NO. 1 TO MEMORANDUM OF UNDERSTANDING
Memorandum of Understanding • October 17th, 2013 • Relypsa Inc • Pharmaceutical preparations

This Amendment No. 1 to Memorandum of Understanding (this “Amendment”) is entered between Relypsa, Inc., having a principal place of business at 700 Saginaw Drive, Redwood City, CA 94063 (“Relypsa”) and LANXESS Corporation, having a principal place of business at 111 RIDC Park West Drive, Pittsburgh, PA 15275 (“LANXESS”) as of June 27, 2013(the “Effective Date”) and amends that certain Memorandum of Understanding between the Parties effective as of November 27, 2012 (the “MOU”). Each party may be referred to herein as a “Party” and collectively the “Parties.”

MEMORANDUM OF UNDERSTANDING
Memorandum of Understanding • October 17th, 2013 • Relypsa Inc • Pharmaceutical preparations

This Memorandum of Understanding (“MOU”), dated November 27, 2012, (the “Effective Date”) is entered into by and between Relypsa, Inc. having a principal place of business at 5301 Patrick Henry Drive, Santa Clara, CA 95054 (“Relypsa”) and LANXESS Corporation, having a principal place of business at 111 RIDC Park West Drive, Pittsburgh, PA 15275 (“LANXESS”); each party referred to as a “Party” and collectively the “Parties”.

AMENDMENT NO. 2 TO MEMORANDUM OF UNDERSTANDING
Memorandum of Understanding • October 17th, 2013 • Relypsa Inc • Pharmaceutical preparations

This Amendment No. 2 to Memorandum of Understanding (“Amendment 2”) is entered between Relypsa, Inc., having a principal place of business at 700 Saginaw Drive, Redwood City, CA 94063 (“Relypsa”) and LANXESS Corporation, having a principal place of business at 111 RIDC Park West Drive, Pittsburgh, PA 15275 (“LANXESS”) as of September 30, 2013 (the “Effective Date”) and amends that certain Memorandum of Understanding between the Parties effective as of November 27, 2012 (the “Original MOU”) as amended by Amendment No. 1 to Memorandum of Understanding effective as of June 27, 2013 (“Amendment 1”) (the Original MOU as amended by Amendment 1, the “MOU”). Each party may be referred to herein as a “Party” and collectively the “Parties.”

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