0001193125-13-481239 Sample Contracts

AUSPEX PHARMACEUTICALS, INC. LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • December 20th, 2013 • Auspex Pharmaceuticals, Inc. • Pharmaceutical preparations • California

This LOAN AND SECURITY AGREEMENT (the “Agreement”) is entered into as of January 9, 2013, by and between Square 1 Bank (“Bank”) and AUSPEX PHARMACEUTICALS, INC. (“Borrower”).

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INDEMNIFICATION AGREEMENT
Indemnification Agreement • December 20th, 2013 • Auspex Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware

THIS INDEMNIFICATION AGREEMENT (this “Agreement”) dated as of , is made by and between AUSPEX PHARMACEUTICALS, INC., A DELAWARE CORPORATION (THE “Company”), and (“Indemnitee”).

AUSPEX PHARMACEUTICALS, INC. AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT December 20, 2013
Investors’ Rights Agreement • December 20th, 2013 • Auspex Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware

This Amended and Restated Investors’ Rights Agreement (the “Agreement”) is made as of December 20, 2013, by and among Auspex Pharmaceuticals, Inc., a Delaware corporation (the “Company”), the holders of the Company’s Series A-1, Series A-2, Series A-3, Series A-4 and Series A-5 Preferred Stock set forth on Exhibit A attached hereto (the “Series A Holders”), the holders of Series B Preferred Stock set forth on Exhibit A attached hereto (the “Series B Holders”), the holders of Series C Preferred Stock set forth on Exhibit A attached hereto (the “Series C Holders”), the holders of Series D Preferred Stock set forth on Exhibit A attached hereto (the “Series D Holders”) and the holders of Series E Preferred Stock set forth on Exhibit A attached hereto (the “Series E Holders,” and together with the Series A Holders, the Series B Holders, the Series C Holders and the Series D Holders, the “Investors”).

Contract
Auspex Pharmaceuticals, Inc. • December 20th, 2013 • Pharmaceutical preparations • California

THIS WARRANT AND THE UNDERLYING SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 (THE “ACT”) AND MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED, ASSIGNED, PLEDGED OR HYPOTHECATED UNLESS AND UNTIL REGISTERED UNDER THE ACT OR UNLESS THE COMPANY HAS RECEIVED AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY AND ITS COUNSEL THAT SUCH REGISTRATION IS NOT REQUIRED.

February 23, 2012 Dr. David Stamler Via Email: dstamler@auspexpharma.com Dear David:
Auspex Pharmaceuticals, Inc. • December 20th, 2013 • Pharmaceutical preparations

This letter will confirm our discussions regarding your Employment Agreement dated February 4, 2011 as amended on August 25, 2011 and will make the following changes effective January 15, 2012.

FIRST AMENDMENT TO LEASE
Lease • December 20th, 2013 • Auspex Pharmaceuticals, Inc. • Pharmaceutical preparations

THIS FIRST AMENDMENT TO LEASE (“First Amendment”) is made and entered into as of the 21st day of June, 2012, by and between MULLROCK 3 TORREY PINES, LLC, a Delaware limited liability company (“Landlord”) and AUSPEX PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

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