0001193125-14-031782 Sample Contracts

CONCERT PHARMACEUTICALS, INC. [•] Shares Common Stock ($0.001 par value per share) UNDERWRITING AGREEMENT [Pricing date]
Underwriting Agreement • February 3rd, 2014 • Concert Pharmaceuticals, Inc. • Pharmaceutical preparations • New York
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January 16, 2014
Concert Pharmaceuticals, Inc. • February 3rd, 2014 • Pharmaceutical preparations
DEVELOPMENT AND LICENSE AGREEMENT
Development and License Agreement • February 3rd, 2014 • Concert Pharmaceuticals, Inc. • Pharmaceutical preparations

This DEVELOPMENT AND LICENSE AGREEMENT (the “Agreement”) is entered into as of February 26, 2013 (the “Effective Date”) by and between CONCERT PHARMACEUTICALS, INC., a Delaware corporation, with its principal place of business at 99 Hayden Avenue, Suite 500, Lexington, MA 02421, USA (“Concert”), and JAZZ PHARMACEUTICALS IRELAND LIMITED, an Irish company, with its principal place of business at Fourth Floor, Connaught House, One Burlington Road, Dublin 4, Ireland (“Jazz”). Concert and Jazz are sometimes referred to herein individually as a “Party” and collectively as the “Parties”.

CONCERT PHARMACEUTICALS, INC. INCENTIVE STOCK OPTION AGREEMENT GRANTED UNDER 2014 STOCK INCENTIVE PLAN
Incentive Stock Option Agreement • February 3rd, 2014 • Concert Pharmaceuticals, Inc. • Pharmaceutical preparations
DEVELOPMENT AND LICENSE AGREEMENT
Development and License Agreement • February 3rd, 2014 • Concert Pharmaceuticals, Inc. • Pharmaceutical preparations

This Development and License Agreement (“Agreement”) dated as of this 28th of February, 2012 (“Effective Date”), is between Concert Pharmaceuticals, Inc., a Delaware corporation having offices located at 99 Hayden Avenue, Suite 500, Lexington, Massachusetts 02421, USA (“Concert”) and Avanir Pharmaceuticals, Inc., a Delaware corporation having offices located at 20 Enterprise, Suite 200, Aliso Viejo, California 92656, USA (“Avanir”). Each of Concert and Avanir may be referred to hereinafter individually as a “Party” and together as the “Parties.”

CONCERT PHARMACEUTICALS, INC. NONSTATUTORY STOCK OPTION AGREEMENT GRANTED UNDER 2014 STOCK INCENTIVE PLAN
Concert Pharmaceuticals, Inc. • February 3rd, 2014 • Pharmaceutical preparations
MASTER DEVELOPMENT AND LICENSE AGREEMENT BETWEEN CONCERT PHARMACEUTICALS, INC., CELGENE INTERNATIONAL SÀRL, AND CELGENE CORPORATION FOR DEUTERATED PRODUCTS DATED AS OF APRIL 4, 2013
Master Development and License Agreement • February 3rd, 2014 • Concert Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

This Master Development and License Agreement (“Agreement”) dated as of this 4th day of April, 2013 (“Effective Date”), is between Concert Pharmaceuticals, Inc., a Delaware corporation having offices located at 99 Hayden Avenue, Suite 500, Lexington, Massachusetts 02421, USA (“Concert”), Celgene International Sàrl, a Swiss corporation located at Route de Perreux 1, 2017 Boudry, Switzerland (“CIS”), and Celgene Corporation, a Delaware corporation located at 86 Morris Avenue, Summit, New Jersey 07901, USA (“Celgene USA”). Each of Concert, CIS, and Celgene USA may be referred to hereinafter individually as a “Party” and together as the “Parties.”

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