0001193125-14-038940 Sample Contracts

SOPHIRIS BIO INC. OMNIBUS AMENDMENT TO COMMON SHARES PURCHASE WARRANTS
Common Shares Purchase • February 6th, 2014 • Sophiris Bio Inc. • Pharmaceutical preparations • British Columbia

THIS OMNIBUS AMENDMENT TO COMMON SHARES PURCHASE WARRANTS (this “Agreement”) is made as of January 31, 2014, by and among SOPHIRIS BIO INC., an organization incorporated under the Company Act of British Columbia, f/k/a Protox Therapeutics Inc. (the “Company”), and WARBURG PINCUS PRIVATE EQUITY X, L.P. and WARBURG PINCUS X PARTNERS, L.P., each a Delaware limited partnership (each a “Holder” and together the “Holders”), to amend those certain Common Shares Purchase Warrants (each a “Warrant” and collectively the “Warrants”) set forth in ATTACHMENT 1 attached hereto. Capitalized terms not otherwise defined herein shall have the meanings ascribed to them in the Warrants.

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