0001193125-14-076949 Sample Contracts

SECOND AMENDMENT TO LEASE
Lease • February 28th, 2014 • Durect Corp • Pharmaceutical preparations

This Second Amendment to Lease (“Second Amendment”), dated November 11, 2013, by and between Handley Management Corporation (“Lessor”), as successor-by-merger to Renault & Handley Employees Investment Co. (the “Original Lessor”), and Durect Corporation, a Delaware corporation (“Lessee”), amends that certain Lease, dated May 14, 2003 (the “Original Lease”), by and between Original Lessor and Lessee, as amended by that certain First Lease Extension, dated December 15, 2008 (the “First Extension”), the Original Lease, as amended by the First Extension, is hereinafter referred to as the “Lease”, for the Premises located at 10260 Bubb Road, Cupertino, California with reference to the following facts:

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