0001193125-14-167552 Sample Contracts

FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • April 29th, 2014 • Cell Therapeutics Inc • Pharmaceutical preparations • California

This FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT (this “Amendment”), dated as of March 25, 2014 (the “First Amendment Date”), is by and among CELL THERAPEUTICS, INC., a Washington corporation (“Cell Therapeutics”), and SYSTEMS MEDICINE LLC, a Delaware limited liability company (“Systems Medicine”; Cell Therapeutics and Systems Medicine are hereinafter referred to individually and collectively, jointly and severally, as “Borrower”), and HERCULES CAPITAL FUNDING TRUST 2012-1 (“Lender”), assignee of HERCULES CAPITAL FUNDING 2012-1 LLC, assignee of HERCULES TECHNOLOGY GROWTH CAPITAL, INC., a Maryland corporation.

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TERMINATION AGREEMENT
Termination Agreement • April 29th, 2014 • Cell Therapeutics Inc • Pharmaceutical preparations • New York

This Termination Agreement (this “Agreement”), effective as of January 3, 2014 (the “Effective Date”), is made by and between Novartis International Pharmaceutical Ltd., a limited company organized and existing under the laws of Bermuda (“Novartis”), and Cell Therapeutics, Inc., a corporation organized and existing under the laws of the State of Washington (“Cell Therapeutics”). Novartis and Cell Therapeutics are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

Contract
Wholesale Distribution Agreement • April 29th, 2014 • Cell Therapeutics Inc • Pharmaceutical preparations

** Indicates that certain information contained herein has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.

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