0001193125-14-188841 Sample Contracts

AMENDMENT NO. 1 TO AGREEMENT AND PLAN OF MERGER AND REORGANIZATION
Agreement and Plan of Merger and Reorganization • May 8th, 2014 • Zalicus Inc. • Pharmaceutical preparations • Delaware

This AMENDMENT NO. 1 TO AGREEMENT AND PLAN OF MERGER AND REORGANIZATION (this “Amendment”) is made as of May 7, 2014, by and between Zalicus Inc., a Delaware corporation (“Phoenix”), and Epirus Biopharmaceuticals, Inc., a Delaware corporation (the “Company”). Capitalized terms used but not defined herein shall have the meanings ascribed thereto in the Agreement and Plan of Merger and Reorganization, dated as of April 15, 2014 (as amended restated or otherwise modified from time to time, the “Merger Agreement”), by and among Phoenix, Merger Sub and the Company.

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