0001193125-14-249278 Sample Contracts

Confidential Treatment Requested. Confidential portions of this document have been redacted and have been separately filed with the Securities and Exchange Commission. DATED JUNE 20, 2013 DISTRIBUTION AND LICENSING AGREEMENT

Distribution and Licensing Agreement • June 25th, 2014 • CareDx, Inc. • Services-medical laboratories • London

• Contract Type
  Distribution and Licensing Agreement
• Filed
  June 25th, 2014
• Company
  CareDx, Inc.
• Industry
  Services-medical laboratories
• Jurisdiction
  London

NOW THEREFORE, in consideration of the mutual covenants contained in this Agreement and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Parties, intending to be legally bound, agree as follows:

AGREEMENT AND PLAN OF MERGER by and among CAREDX, INC., MONITOR ACQUISITION CORPORATION, IMMUMETRIX, INC., and MATTIAS WESTMAN, AS HOLDERS’ AGENT Dated as of May 17, 2014

Merger Agreement • June 25th, 2014 • CareDx, Inc. • Services-medical laboratories • Delaware

• Contract Type
  Merger Agreement
• Filed
  June 25th, 2014
• Company
  CareDx, Inc.
• Industry
  Services-medical laboratories
• Jurisdiction
  Delaware

This AGREEMENT AND PLAN OF MERGER, made and entered into as of May 17, 2014 (as amended, supplemented or otherwise modified from time to time, this “Agreement”), is by and among CareDx, Inc., a Delaware corporation (“Parent”), Monitor Acquisition Corporation, a Delaware corporation and a wholly owned subsidiary of Parent (“Merger Sub”), ImmuMetrix, Inc., a Delaware corporation (“Company”), and Mattias Westman as the Holders’ Agent, for the purposes of Article VII only. Certain capitalized terms used herein have the meanings assigned to in Annex A.

AMENDMENT NO. 1 TO AGREEMENT AND PLAN OF MERGER

Agreement and Plan of Merger • June 25th, 2014 • CareDx, Inc. • Services-medical laboratories

• Contract Type
  Agreement and Plan of Merger
• Filed
  June 25th, 2014
• Company
  CareDx, Inc.
• Industry
  Services-medical laboratories

This Amendment No. 1 to the Agreement and Plan of Merger (this “Amendment”) is made as of June 9, 2014, by and among CareDx, Inc., a Delaware corporation (the “Parent”), Monitor Acquisition Corporation, a Delaware Corporation and a wholly-owned subsidiary of Parent (the “Merger Sub”), ImmuMetrix, Inc., a Delaware corporation (the “Company”) and Mattias Westman as the Holders’ Agent and amends that certain Agreement and Plan of Merger dated May 17, 2014 (the Agreement”) by and among the Parent, Merger Sub, Company and Mattias Westman.