0001193125-14-398480 Sample Contracts

WARRANT AGREEMENT To Purchase Shares of Common Stock of AVEO PHARMACEUTICALS, INC. Dated as of September 24, 2014 (the “Effective Date”)
Warrant Agreement • November 5th, 2014 • Aveo Pharmaceuticals Inc • Pharmaceutical preparations • California

WHEREAS, AVEO Pharmaceuticals, Inc., a Delaware corporation (the “Company”) and Hercules Technology II, L.P., a Delaware limited partnership and Hercules Technology III, L.P., a Delaware limited partnership (the “Warrantholder”) are parties to a certain Loan and Security Agreement, dated as of May 28, 2010, as amended by that certain Amendment No. 1 to Loan and Security Agreement, dated as of December 21, 2011, and as further amended by that certain Amendment No. 2 to Loan and Security Agreement, dated as of March 31, 2012 (together referred to herein as the “Original Loan Agreement”);

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Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. AMENDMENT NO. 3 TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • November 5th, 2014 • Aveo Pharmaceuticals Inc • Pharmaceutical preparations • California

This AMENDMENT NO. 3 TO LOAN AND SECURITY AGREEMENT (this “Amendment”), is entered into this 24th day of September, 2014, by and among AVEO PHARMACEUTICALS, INC., a Delaware corporation (“Borrower”), and HERCULES TECHNOLOGY GROWTH CAPITAL, INC., a Maryland corporation (“HTGC Inc.”), HERCULES CAPITAL FUNDING TRUST 2012-1, a statutory trust created and existing under the laws of the State of Delaware (“Trust”), and HERCULES TECHNOLOGY III, L.P., a Delaware limited partnership (“Hercules III”, together with HTGC Inc. and Trust collectively referred to as the “Lender”).

THIRD AMENDMENT TO LEASE AND LEASE TERMINATION AGREEMENT
Lease Agreement • November 5th, 2014 • Aveo Pharmaceuticals Inc • Pharmaceutical preparations

THIS THIRD AMENDMENT TO LEASE AND LEASE TERMINATION AGREEMENT (this “Amendment”) is entered into as of this 24th day of September, 2014 (the “Execution Date”), by and between BMR-650 E KENDALL B LLC, a Delaware limited liability company (“Landlord”), and AVEO PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

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