0001193125-15-177372 Sample Contracts

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • May 7th, 2015 • Tobira Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This Registration Rights Agreement (the “Agreement”) is made and entered into as of this 4th day of May, 2015 by and among Regado Biosciences, Inc. (which name will be changed to Tobira Therapeutics, Inc. upon the closing of the Merger, each as defined below), a Delaware corporation (the “Company”), and the “Investors” named in that certain Purchase Agreement by and among the Company and the Investors of even date herewith (the “Purchase Agreement”). This Agreement is made pursuant to the Purchase Agreement and shall be effective as of the Closing. Capitalized terms used herein have the respective meanings ascribed thereto in the Purchase Agreement unless otherwise defined herein.

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PURCHASE AGREEMENT
Purchase Agreement • May 7th, 2015 • Tobira Therapeutics, Inc. • Pharmaceutical preparations • Delaware

THIS PURCHASE AGREEMENT (this “Agreement”) is made as of the 4th day of May, 2015 by and among Regado Biosciences, Inc (which name will be changed to Tobira Therapeutics, Inc. upon the Closing of the Merger, each as defined below), a Delaware corporation (the “Company”), and the Investors set forth on the signature pages affixed hereto (each, including its successors and assigns, an “Investor” and collectively, the “Investors”).

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