0001193125-15-212645 Sample Contracts

BIOTIE THERAPIES CORP. [●] Ordinary Shares to be represented by [●] American Depositary Shares FORM OF UNDERWRITING AGREEMENT
Underwriting Agreement • June 4th, 2015 • Biotie Therapies Corp. • Pharmaceutical preparations • New York

Biotie Therapies Corp., a public limited liability company organized under the laws of the Republic of Finland (the “Company”), proposes to issue to the several underwriters named in Schedule I hereto (the “Underwriters”) for whom RBC Capital Markets, LLC and Stifel, Nicolaus & Company, Incorporated are acting as representatives (the “Representatives”) an aggregate of [●] ordinary shares, no nominal value per share, of the Company (“Ordinary Shares”), which will be represented by [●] American Depositary Shares (“American Depositary Shares,” and such American Depositary Shares, the “Firm ADSs”). The Company also proposes to issue to the several Underwriters up to an additional [●] Ordinary Shares which will be represented by [●] American Depositary Shares (the “Option ADSs”). The Firm ADSs and the Option ADSs are hereinafter referred to collectively as the “ADSs.” The Ordinary Shares which will be represented by the ADSs are herein called the “Underlying Shares”. Each ADS will initially

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REGISTRATION RIGHTS AGREEMENT dated as of May 28, 2015 among BIOTIE THERAPIES CORP. and THE INVESTORS PARTY HERETO
Registration Rights Agreement • June 4th, 2015 • Biotie Therapies Corp. • Pharmaceutical preparations • New York
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