0001193125-15-282067 Sample Contracts

LEASE by and between BMR-675 WEST KENDALL STREET LLC, a Delaware limited liability company and ALNYLAM PHARMACEUTICALS, INC., a Delaware corporation
Lease • August 7th, 2015 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations

IN WITNESS WHEREOF, Tenant has executed this Acknowledgment of Term Commencement Date and Term Expiration Date as of the date first written above.

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LEASE RREEF AMERICA REIT II CORP. PPP, Landlord, and ALNYLAM PHARMACEUTICALS, INC., Tenant Riverfront Office Park Cambridge, Massachusetts
Lease • August 7th, 2015 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations

By this Lease Landlord leases to Tenant and Tenant leases from Landlord the Premises in the Building as set forth and described on the Reference Pages. The Premises are depicted on the floor plan attached hereto as Exhibit A, and the Building is depicted on the site plan attached hereto as Exhibit A-1. The Building is located on the Lot legally described on Exhibit A-2. The Reference Pages, including all terms defined thereon, are incorporated as part of this Lease.

ALNYLAM PHARMACEUTICALS, INC. Incentive Stock Option Agreement Granted Under Amended and Restated 2009 Stock Incentive Plan
Incentive Stock Option Agreement • August 7th, 2015 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations
ALNYLAM PHARMACEUTICALS, INC. Nonstatutory Stock Option Agreement Granted Under Amended and Restated 2009 Stock Incentive Plan
Stock Option Agreement • August 7th, 2015 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations
ALNYLAM PHARMACEUTICALS, INC. Restricted Stock Agreement
Restricted Stock Agreement • August 7th, 2015 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware

Alnylam Pharmaceuticals, Inc. (the “Company”) has selected you to receive the restricted stock award described above, which is subject to the provisions of the Company’s Amended and Restated 2009 Stock Incentive Plan (the “Plan”) and the terms and conditions contained in this Restricted Stock Agreement. Electronic acceptance of this Agreement pursuant to the Company’s instructions (including through an online acceptance process) is acceptable. Please confirm your acceptance of this restricted stock award and of the terms and conditions of this Agreement by signing a copy of this Agreement where indicated below.

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