0001193125-15-304421 Sample Contracts

SECOND AMENDED AND RESTATED AGREEMENT AND PLAN OF MERGER by and among INSITE VISION INCORPORATED, QLT INC. and ISOTOPE ACQUISITION CORP. Dated as of June 8, 2015, as amended and restated August 26, 2015
Agreement and Plan of Merger • August 27th, 2015 • Insite Vision Inc • Pharmaceutical preparations • Delaware

This SECOND AMENDED AND RESTATED AGREEMENT AND PLAN OF MERGER (this “Agreement”), dated as of August 26, 2015 (the “Execution Date”), is by and among INSITE VISION INCORPORATED, a Delaware corporation (the “Company”), QLT INC., a corporation incorporated under the laws of British Columbia (“Parent”), and ISOTOPE ACQUISITION CORP., a Delaware corporation and a wholly owned indirect Subsidiary of Parent (“Merger Sub” and, together with Parent and the Company, the “Parties” and each, individually, a “Party”), and amends and restates in its entirety that certain Agreement and Plan of Merger, dated June 8, 2015, as amended and restated July 16, 2015.

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