0001193125-15-370112 Sample Contracts

AMENDED AND RESTATED COMMERCIAL LICENSE AGREEMENT
Commercial License Agreement • November 6th, 2015 • Sage Therapeutics, Inc. • Pharmaceutical preparations • California

CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT WERE OMITTED AND REPLACED WITH “[***]”. A COMPLETE VERSION OF THIS EXHIBIT HAS BEEN FILED SEPARATELY WITH THE SECRETARY OF THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO AN APPLICATION REQUESTING CONFIDENTIAL TREATMENT PURSUANT TO RULE 24B-2 PROMULGATED UNDER THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED.

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AMENDMENT NO. 3 TO SUPPLY AGREEMENT
Supply Agreement • November 6th, 2015 • Sage Therapeutics, Inc. • Pharmaceutical preparations

THIS AMENDMENT NO. 3 TO SUPPLY AGREEMENT (this “Amendment”) is entered into on this 25th day of September, 2015 (the “2015 Date”), with retroactive effect to April 30, 2014 (the “Amendment Effective Date”) between:

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