REPLIGEN CORPORATION AND WILMINGTON TRUST, NATIONAL ASSOCIATION, as Trustee FIRST SUPPLEMENTAL INDENTURE Dated as of May 24, 2016 to Indenture for Senior Debt Securities Dated as of May 24, 2016 2.125% Convertible Senior Notes due 2021First Supplemental Indenture • May 24th, 2016 • Repligen Corp • Biological products, (no disgnostic substances) • New York
FIRST SUPPLEMENTAL INDENTURE dated as of May 24, 2016 (this “Supplemental Indenture”), between REPLIGEN CORPORATION, a Delaware corporation, as issuer (the “Company,” as more fully set forth in Section 1.01) and WILMINGTON TRUST, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee,” as more fully set forth in Section 1.01), supplementing the Indenture for Senior Debt Securities dated as of May 24, 2016, between the Company and the Trustee (the “Base Indenture” and the Base Indenture, as amended and supplemented by this Supplemental Indenture, and as it may be further amended or supplemented from time to time with respect to the Notes, the “Indenture”).
