ARRANGEMENT AGREEMENT BY AND AMONG OPKO HEALTH, INC., OPKO GLOBAL HOLDINGS, INC. AND TRANSITION THERAPEUTICS INC. Dated as of June 29, 2016Arrangement Agreement • June 30th, 2016 • Opko Health, Inc. • Pharmaceutical preparations • Ontario
Contract Type FiledJune 30th, 2016 Company Industry JurisdictionTHIS ARRANGEMENT AGREEMENT (this “Agreement”) is made and entered into as of June 29, 2016, by and among OPKO HEALTH, INC., a Delaware corporation (“Parent”); OPKO GLOBAL HOLDINGS, INC., a corporation incorporated under the laws of the Cayman Islands (“CaymanCo”); and TRANSITION THERAPEUTICS INC., a corporation incorporated under the laws of Ontario (the “Company”). Certain capitalized terms used in this Agreement are defined in Section 8.1.