0001193125-16-673277 Sample Contracts

EMPLOYMENT AGREEMENT
Employment Agreement • August 5th, 2016 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations • California

This Employment Agreement (“Agreement”) is entered into as of February 3, 2015 (the “Effective Date”), by and between Jason Keyes (“Executive”) and Orexigen Therapeutics, Inc. (the “Company”).

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OREXIGEN THERAPEUTICS, INC. AMENDMENT NO. 2 TO EMPLOYMENT AGREEMENT JUNE 16, 2016
Employment Agreement • August 5th, 2016 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations • California

Reference is made to the EMPLOYMENT AGREEMENT (the “Agreement”) dated March 30, 2015 by and between OREXIGEN THERAPEUTICS, INC. (“Orexigen” or the “Company”) with its principal place of business located at 3344 N. Torrey Pines Ct., Suite 200, La Jolla, CA 92037 and THOMAS CANNELL (“Executive”), and AMENDMENT NO. 1 TO THE EMPLOYMENT AGREEMENT dated February 2, 2016 (the “First Amendment”). All capitalized terms used herein and not otherwise defined shall have the meanings assigned to such terms in the Agreement.

OREXIGEN THERAPEUTICS, INC. AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT FEBRUARY 2, 2016
Employment Agreement • August 5th, 2016 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations • California

This Amendment No. 1 is intended to modify the EMPLOYMENT AGREEMENT (the “Agreement”) dated February 3, 2015 by and between OREXIGEN THERAPEUTICS, INC. (“Orexigen” or the “Company”) with its principal place of business located at 3344 N. Torrey Pines Ct., Suite 200, La Jolla, CA 92037 and JASON KEYES (“Executive”). All capitalized terms used herein and not otherwise defined shall have the meanings assigned to such terms in the Agreement.

OREXIGEN THERAPEUTICS, INC. AMENDMENT NO. 2 TO EMPLOYMENT AGREEMENT JUNE 16, 2016
Employment Agreement • August 5th, 2016 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations • California

Reference is made to the EMPLOYMENT AGREEMENT (the “Agreement”) dated February 3, 2015 by and between OREXIGEN THERAPEUTICS, INC. (“Orexigen” or the “Company”) with its principal place of business located at 3344 N. Torrey Pines Ct., Suite 200, La Jolla, CA 92037 and JASON KEYES (“Executive”), and AMENDMENT NO. 1 TO THE EMPLOYMENT AGREEMENT dated February 2, 2016 (the “First Amendment”). All capitalized terms used herein and not otherwise defined shall have the meanings assigned to such terms in the Agreement.

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