INOTEK PHARMACEUTICALS CORPORATION AND WILMINGTON TRUST, NATIONAL ASSOCIATION, as Trustee FIRST SUPPLEMENTAL INDENTURE Dated as of August 5, 2016 to Indenture for Senior Debt Securities Dated as of August 5, 2016 5.75% Convertible Senior Notes due 2021First Supplemental Indenture • August 5th, 2016 • Inotek Pharmaceuticals Corp • Pharmaceutical preparations • New York
FIRST SUPPLEMENTAL INDENTURE dated as of August 5, 2016 (this “Supplemental Indenture”), between INOTEK PHARMACEUTICALS CORPORATION, a Delaware corporation, as issuer (the “Company,” as more fully set forth in Section 1.01) and WILMINGTON TRUST, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee,” as more fully set forth in Section 1.01), supplementing the Indenture for Senior Debt Securities dated as of August 5, 2016, between the Issuer and the Trustee (the “Base Indenture” and the Base Indenture, as amended and supplemented by this Supplemental Indenture, and as it may be further amended or supplemented from time to time with respect to the Notes, the “Indenture”).
