0001193125-16-763038 Sample Contracts

SECURITY AGREEMENT
Patent Security Agreement • November 8th, 2016 • Heron Therapeutics, Inc. /De/ • Pharmaceutical preparations

This SECURITY AGREEMENT (this “Agreement”), dated as of August 5, 2016 among HERON THERAPEUTICS, INC., a Delaware corporation (the “Heron”), and those additional entities that hereafter become parties hereto by executing the form of Supplement attached hereto as Annex 1 (together with Heron, individually and collectively, the “Grantor”), TANG CAPITAL PARTNERS, LP, in its capacity as the Holder (as defined in the Note), and TC MANAGEMENT SERVICES, LLC as the collateral agent (together with its successors, “Agent”).

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LEASE GENESIS CAMPUS POINT AP3-SD1 CAMPUS POINT LLC, a Delaware limited liability company as Landlord, and HERON THERAPEUTICS, INC., a Delaware corporation as Tenant
Genesis Campus Point • November 8th, 2016 • Heron Therapeutics, Inc. /De/ • Pharmaceutical preparations • California

This Lease (the “Lease”), dated as of the date set forth in Section 1 of the Summary of Basic Lease Information (the “Summary”), below, is made by and between AP3-SD1 CAMPUS POINT LLC, a Delaware limited liability company (“Landlord”), and HERON THERAPEUTICS, INC., a Delaware corporation (“Tenant”).

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