0001193125-17-084391 Sample Contracts

Dated: March 16, 2017 Thermo Fisher Scientific Inc. as Issuer and The Bank of New York Mellon, London Branch as Paying Agent PAYING AGENCY AGREEMENT
Paying Agency Agreement • March 16th, 2017 • Thermo Fisher Scientific Inc. • Measuring & controlling devices, nec • New York

THIS AGREEMENT is made as of March 16, 2017 between Thermo Fisher Scientific Inc., a Delaware corporation (the “Issuer”), and The Bank of New York Mellon, London Branch, as paying agent (the “Paying Agent”), located at One Canada Square, London E14 5AL.

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THERMO FISHER SCIENTIFIC INC., as Issuer AND THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., as Trustee FIFTEENTH SUPPLEMENTAL INDENTURE Dated as of March 16, 2017 €500,000,000 of 1.450% Senior Notes due 2027
Fifteenth Supplemental Indenture • March 16th, 2017 • Thermo Fisher Scientific Inc. • Measuring & controlling devices, nec • New York

THIS FIFTEENTH SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”) is dated as of March 16, 2017 between THERMO FISHER SCIENTIFIC INC., a Delaware corporation (the “Company”), and THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., a national banking association, as trustee (the “Trustee”).

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