0001193125-17-195961 Sample Contracts

UNDERWRITING AGREEMENT 3,000,000 Shares AEGLEA BIOTHERAPEUTICS, INC. Common Stock ($0.0001 Par Value) EQUITY UNDERWRITING AGREEMENT
Underwriting Agreement • June 6th, 2017 • Aeglea BioTherapeutics, Inc. • Pharmaceutical preparations • New York

Aeglea BioTherapeutics, Inc., a Delaware corporation (the “Company”), proposes to sell to JonesTrading Institutional Services LLC (the “Underwriter”) an aggregate 3,000,000 shares (the “Firm Shares”) of the Company’s common stock, $0.0001 par value (the “Common Stock”). The Company also proposes to sell at the Underwriter’s option an aggregate of up to 450,000 additional shares of the Company’s Common Stock (the “Option Shares”) as set forth below. The Firm Shares and the Option Shares (to the extent the aforementioned option is exercised) are herein collectively called the “Shares”.

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