SPARK THERAPEUTICS, INC. 4,605,264 Shares of Common Stock, par value $0.001 per share Underwriting AgreementSpark Therapeutics, Inc. • August 4th, 2017 • Biological products, (no disgnostic substances) • New York
Company FiledAugust 4th, 2017 Industry JurisdictionSpark Therapeutics, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several Underwriters listed in Schedule 1 hereto (the “Underwriters”), for whom you are acting as representative (the “Representative”), an aggregate of 4,605,264 shares of Common Stock, par value $0.001 per share, of the Company (the “Underwritten Shares”). In addition, the Company proposes to issue and sell, at the option of the Underwriters, up to an additional 690,789 shares of Common Stock of the Company (the “Option Shares”). The Underwritten Shares and the Option Shares are herein referred to as the “Shares”. The shares of Common Stock of the Company to be outstanding after giving effect to the sale of the Shares are referred to herein as the “Stock”.