0001193125-17-252750 Sample Contracts

DOUBLE EAGLE ACQUISITION SUB, INC., the GUARANTORS party hereto from time to time AND WILMINGTON TRUST, NATIONAL ASSOCIATION, as Trustee 7.500% Senior Notes due 2024 INDENTURE Dated as of October 14, 2016
Indenture • August 9th, 2017 • INC Research Holdings, Inc. • Services-commercial physical & biological research • New York

INDENTURE dated as of October 14, 2016, among DOUBLE EAGLE ACQUISITION SUB, INC. (the “Issuer”), the Guarantors party hereto from time to time and WILMINGTON TRUST, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee”).

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SECOND SUPPLEMENTAL INDENTURE
Second Supplemental Indenture • August 9th, 2017 • INC Research Holdings, Inc. • Services-commercial physical & biological research • New York

Second Supplemental Indenture, dated as of August 7, 2017 (this “Second Supplemental Indenture”), among INC Research Holdings, Inc., a Delaware corporation (“INC”), inVentiv Health, Inc., a Delaware corporation (“inVentiv Health”), inVentiv Health Clinical, Inc., a Delaware corporation (“inVentiv Clinical”), the guarantors named in the signature pages hereto as New Guarantors (the “New Guarantors”), the guarantors named in the signature pages hereto as Existing Guarantors (the “Existing Guarantors” and together with the New Guarantors, the “Guarantors”) and Wilmington Trust, National Association, as trustee (the “Trustee”).

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