0001193125-17-264395 Sample Contracts

Laboratory Corporation of America Holdings $600,000,000 3.250% Senior Notes Due 2024 $600,000,000 3.600% Senior Notes Due 2027 Underwriting Agreement
Underwriting Agreement • August 22nd, 2017 • Laboratory Corp of America Holdings • Services-medical laboratories • New York

Laboratory Corporation of America Holdings, a corporation organized under the laws of Delaware (the “Company”), proposes to sell to the several underwriters named in Schedule II hereto (the “Underwriters”), for whom you (“you” or the “Representatives”) are acting as representatives, the principal amount of its notes identified in Schedule I hereto (the “Notes”), to be issued under an indenture dated as of November 19, 2010 as supplemented by the Eleventh Supplemental Indenture to be dated August 22, 2017 and the Twelfth Supplemental Indenture to be dated August 22, 2017 (collectively, the “Indenture”), each between the Company and U.S. Bank National Association, as trustee (the “Trustee”). To the extent there are no additional Underwriters named in Schedule II other than you, the term Representatives as used herein shall mean you, as Underwriters, and the terms Representatives and Underwriters shall mean either the singular or plural as the context requires. Any reference herein to the

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3.250% SENIOR NOTES DUE 2024 LABORATORY CORPORATION OF AMERICA HOLDINGS as Issuer AND U.S. BANK NATIONAL ASSOCIATION as Trustee ELEVENTH SUPPLEMENTAL INDENTURE DATED AS OF AUGUST 22, 2017
Eleventh Supplemental Indenture • August 22nd, 2017 • Laboratory Corp of America Holdings • Services-medical laboratories • New York

ELEVENTH SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of August 22, 2017 between Laboratory Corporation of America Holdings, a Delaware corporation (or its permitted successor) (the “Company”), and U.S. Bank National Association, as Trustee under the Indenture (the “Trustee”).

3.600% SENIOR NOTES DUE 2027 LABORATORY CORPORATION OF AMERICA HOLDINGS as Issuer AND U.S. BANK NATIONAL ASSOCIATION as Trustee TWELFTH SUPPLEMENTAL INDENTURE DATED AS OF AUGUST 22, 2017
Twelfth Supplemental Indenture • August 22nd, 2017 • Laboratory Corp of America Holdings • Services-medical laboratories • New York

TWELFTH SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of August 22, 2017 between Laboratory Corporation of America Holdings, a Delaware corporation (or its permitted successor) (the “Company”), and U.S. Bank National Association, as Trustee under the Indenture (the “Trustee”).

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