0001193125-17-309813 Sample Contracts

BLUEGRASS EYE BUILDING OFFICE LEASE AGREEMENT BY AND BETWEEN DHB PROPERTIES. LLC, A KENTUCKY PROFESSIONAL SERVICE CORPORATION (“LANDLORD”) AND APELLIS PHARMACUTICALS, INC. A DELAWARE CORPORATION (“TENANT”) DATED OCTOBER 21, 2010

Office Lease Agreement • October 13th, 2017 • Apellis Pharmaceuticals, Inc. • Pharmaceutical preparations • Kentucky

• Contract Type
  Office Lease Agreement
• Filed
  October 13th, 2017
• Company
  Apellis Pharmaceuticals, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Kentucky

THIS OFFICE LEASE AGREEMENT (“Lease”) is entered into and made this day of October, 2010, by and between (i) DHB PROPERTIES, LLC, a Kentucky professional services corporation (“Landlord”), and (ii) APELLIS PHARMACEUTICALS, INC, a Delaware corporation (“Tenant”).

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. CONFIDENTIAL UNIVERSITY of PENNSYLVANIA Patent License Agreement

Stockholders Agreement • October 13th, 2017 • Apellis Pharmaceuticals, Inc. • Pharmaceutical preparations • Pennsylvania

• Contract Type
  Stockholders Agreement
• Filed
  October 13th, 2017
• Company
  Apellis Pharmaceuticals, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Pennsylvania

THIS THIRD AMENDED AND RESTATED STOCKHOLDERS AGREEMENT (this “Agreement”) is entered into as of March , 2008, by and among Potentia Pharmaceuticals, Inc., a Delaware corporation (the “Company”) and those individuals identified on Exhibit A hereto (individually, each a “Stockholder” and collectively, the “Stockholders”).

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. CONFIDENTIAL UNIVERSITY OF PENNSYLVANIA Amended and Restated Patent License Agreement

Patent License Agreement • October 13th, 2017 • Apellis Pharmaceuticals, Inc. • Pharmaceutical preparations • Pennsylvania

• Contract Type
  Patent License Agreement
• Filed
  October 13th, 2017
• Company
  Apellis Pharmaceuticals, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Pennsylvania

THIS THIRD AMENDED AND RESTATED STOCKHOLDERS AGREEMENT (this “Agreement”) is entered into as of March , 2008, by and among Potentia Pharmaceuticals, Inc., a Delaware corporation (the “Company”) and those individuals identified on Exhibit A hereto (individually, each a “Stockholder” and collectively, the “Stockholders”).

ASSET PURCHASE AGREEMENT dated September 24, 2014 between APELLIS PHARMACEUTICALS, INC. and POTENTIA PHARMACEUTICALS, INC.

Asset Purchase Agreement • October 13th, 2017 • Apellis Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware

• Contract Type
  Asset Purchase Agreement
• Filed
  October 13th, 2017
• Company
  Apellis Pharmaceuticals, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

This Asset Purchase Agreement is entered into as of September 24, 2014 by and between Apellis Pharmaceuticals, Inc., a Delaware corporation (the “Buyer”), and Potentia Pharmaceuticals, Inc., a Delaware corporation (the “Seller”).

CONSULTING AGREEMENT

Consulting Agreement • October 13th, 2017 • Apellis Pharmaceuticals, Inc. • Pharmaceutical preparations • Massachusetts

• Contract Type
  Consulting Agreement
• Filed
  October 13th, 2017
• Company
  Apellis Pharmaceuticals, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Massachusetts

This Consulting Agreement (the “Agreement”) is made effective as of August 20, 2015 (the “Effective Date”), by and between Apellis Pharmaceuticals, Inc., a Delaware corporation, with its principal place of business being 6400 Westwind Way, Suite A, Crestwood, Kentucky, 40014 (the “Company”) and Danforth Advisors, LLC, a Massachusetts limited liability corporation, with its principal place of business being 91 Middle Road, Southborough, MA 01772 (“Danforth”). The Company and Danforth are herein sometimes referred to individually as a “Party” and collectively as the “Parties.”