0001193125-17-342602 Sample Contracts

AMENDMENT NO. 1 TO AT MARKET ISSUANCE SALES AGREEMENT
At Market Issuance Sales Agreement • November 14th, 2017 • Evoke Pharma Inc • Pharmaceutical preparations • New York

Evoke Pharma, Inc. (the “Company”) and B. Riley FBR, as successor by merger to FBR Capital Markets & Co. (“B. Riley FBR”) are parties to that certain At Market Issuance Sales Agreement dated April 15, 2016 (the “Original Agreement”). All capitalized terms not defined herein shall have the meanings ascribed to them in the Original Agreement. The parties, intending to be legally bound, hereby amend the Original Agreement as follows (to be effective as set forth in paragraph 6 below):

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