0001193125-18-016749 Sample Contracts

FIRST AMENDMENT TO LEASE AGREEMENT
Lease Agreement • January 23rd, 2018 • Spero Therapeutics, Inc. • Pharmaceutical preparations

This FIRST AMENDMENT TO LEASE (the “Amendment”) dated this 17th day of January, 2018 (the “Effective Date”) is made by and between U.S. REIF CENTRAL PLAZA MASSACHUSETTS, LLC, a Delaware limited liability company (the “Landlord”), and SPERO THERAPEUTICS, INC. (formerly known as Spero Opco, Inc.), a Delaware corporation (the “Tenant”).

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