0001193125-18-099776 Sample Contracts

APTOSE BIOSCIENCES INC. Common Shares (no par value per share) Controlled Equity OfferingSM Sales Agreement
Aptose Biosciences Inc. • March 28th, 2018 • Biological products, (no disgnostic substances) • New York

Aptose Biosciences Inc., a company incorporated under the Canada Business Corporations Act (the “Company”), confirms its agreement (this “Agreement”) with Cantor Fitzgerald & Co. (the “Agent”), as follows:

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