0001193125-18-140612 Sample Contracts

EVELO BIOSCIENCES, INC. INDEMNIFICATION AGREEMENT
Indemnification Agreement • April 30th, 2018 • Evelo Biosciences, Inc. • Pharmaceutical preparations • Delaware

THIS INDEMNIFICATION AGREEMENT (the “Agreement”) is made and entered into as of ______________, 20[18] between Evelo Biosciences, Inc., a Delaware corporation (the “Company”), and [Name] (“Indemnitee”).

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] Shares EVELO BIOSCIENCES, INC. COMMON STOCK (PAR VALUE $0.001 PER SHARE) UNDERWRITING AGREEMENT
Underwriting Agreement • April 30th, 2018 • Evelo Biosciences, Inc. • Pharmaceutical preparations • New York

This letter is being delivered to you in connection with the offering by Evelo Biosciences, Inc. (the “Company”) of shares of common stock, par value $0.001 per share (the “Common Stock”), of the Company and the lock-up letter dated , 20 (the “Lock-up Letter”), executed by you in connection with such offering, and your request for a [waiver] [release] dated , 20 , with respect to shares of Common Stock (the “Shares”).

FOURTH AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • April 30th, 2018 • Evelo Biosciences, Inc. • Pharmaceutical preparations • Massachusetts

THIS FOURTH AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT (the “Agreement”) is made as of February 9, 2018, by and among Evelo Biosciences, Inc., a Delaware corporation (the “Company”), and each of the investors listed on Schedule A hereto (each, an “Investor,” and together with any subsequent investors, or transferees, who become parties hereto as “Investors” pursuant to Subsection 6.9, the “Investors”).

Confidential Treatment Requested Evelo Biosciences, Inc. EXCLUSIVITY AND COMMITMENT AGREEMENT
Exclusivity and Commitment Agreement • April 30th, 2018 • Evelo Biosciences, Inc. • Pharmaceutical preparations • England

This Exclusivity and Commitment Agreement (the “Agreement”) is entered into as of February 15, 2018 (the “Effective Date”), by and between Biose Industrie, a French corporation with offices at Rue des Freres Lumieres 15130 Arpajon sur Cere France registered under number B 529 243 271 (“Biose” or “Company”) and Evelo Biosciences, Inc., a Delaware company with a principal place of business at 620 Memorial Drive, Cambridge, Massachusetts 02139 USA (“Evelo”). Evelo and Biose are each individually a “Party” and collectively referred as “Parties”.

EXCLUSIVE LICENSE AGREEMENT BETWEEN THE UNIVERSITY OF CHICAGO AND EVELO BIOSCIENCES FOR AN IMMUNO-ONCOLOGY TECHNOLOGY
Exclusive License Agreement • April 30th, 2018 • Evelo Biosciences, Inc. • Pharmaceutical preparations

This License Agreement (“Agreement”), dated March 10, 2016 (the “Effective Date”), is between The University of Chicago, an Illinois not-for-profit corporation (“University”), and Evelo Biosciences, Inc., a Delaware corporation, having an address at 620 Memorial Drive, Suite 200 Cambridge, Massachusetts 02139. (“Company”). Each hereunder may be referred to separately as the “Party”, or together as the “Parties”.

Confidential Treatment Requested Evelo Biosciences, Inc. MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH PATENT LICENSE AGREEMENT
Patent License Agreement • April 30th, 2018 • Evelo Biosciences, Inc. • Pharmaceutical preparations • Minnesota

This patent license agreement (“Agreement”) is by and between Mayo Foundation for Medical Education and Research, a Minnesota charitable corporation, located at 200 First Street SW, Rochester, Minnesota 55905-0001 (“MAYO”), and Evelo Biosciences, Inc. (“COMPANY”), a Delaware corporation, having a place of business at 620 Memorial Drive, Suite 200 West, Cambridge, Massachusetts 02139, each a “Party,” and collectively “Parties”.

EVELO BIOSCIENCES, INC. LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • April 30th, 2018 • Evelo Biosciences, Inc. • Pharmaceutical preparations • North Carolina

This LOAN AND SECURITY AGREEMENT (the “Agreement”) is entered into as of August 15, 2016, by and between PACIFIC WESTERN BANK, a California state chartered bank (“Bank”) and EVELO BIOSCIENCES, INC., a Delaware corporation (“Borrower”).

DATED Weatherden Limited and Evelo Biosciences, Inc. AGREEMENT FOR THE SUPPLY OF SERVICES
Evelo Biosciences, Inc. • April 30th, 2018 • Pharmaceutical preparations
SUBLEASE AGREEMENT
Sublease Agreement • April 30th, 2018 • Evelo Biosciences, Inc. • Pharmaceutical preparations • Massachusetts

This Sublease Agreement (”Sublease”), dated December 27, 2017 (the “Effective Date”), is by and between Bio-Rad Laboratories, Inc., a Delaware corporation, having its principle place of business at 1000 Alfred Nobel Drive, Hercules, California 94547 (”Sublandlord”), and Evelo Biosciences, Inc., a Delaware corporation, having an office at 620 Memorial Dr. #200, Cambridge, MA 02139 (”Subtenant”);

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