0001193125-18-189404 Sample Contracts

ALPINE IMMUNE SCIENCES, INC. EQUITY DISTRIBUTION AGREEMENT
Equity Distribution Agreement • June 11th, 2018 • Alpine Immune Sciences, Inc. • Pharmaceutical preparations • New York

As further set forth in this equity distribution agreement (this “Agreement”), Alpine Immune Sciences, Inc., a Delaware corporation (the “Company”), proposes to issue and sell from time to time through Piper Jaffray & Co. (the “Agent”), as sales agent, the Company’s common stock, par value $0.001 per share (the “Common Stock”) (such shares of Common Stock to be sold pursuant to this Agreement, the “Shares”) on the terms set forth herein. Notwithstanding anything to the contrary contained herein, the parties hereto agree that compliance with the limitation set forth in Section 2 hereof on the number of Shares issued and sold hereunder shall be the sole responsibility of the Company, and the Agent shall have no obligation in connection therewith.

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