0001193125-18-241955 Sample Contracts

Dated: August 8, 2018 Thermo Fisher Scientific (Finance I) B.V. as Issuer and The Bank of New York Mellon, London Branch as Paying Agent PAYING AGENCY AGREEMENT
Paying Agency Agreement • August 8th, 2018 • Thermo Fisher Scientific Inc. • Measuring & controlling devices, nec • New York

THIS AGREEMENT is made as of August 8, 2018 between Thermo Fisher Scientific (Finance I) B.V., a private company with limited liability (besloten vennootschap met beperkte aansprakelijkheid) incorporated under the laws of the Netherlands, with its corporate seat (statutaire zetel) at Breda, The Netherlands, and its registered office at Takkebijsters 1, 4817 BL Breda, The Netherlands, registered with the Dutch Trade Register of the Chamber of Commerce under number 66428319 (the “Issuer”), and The Bank of New York Mellon (London Branch), as paying agent (the “Paying Agent”), located at One Canada Square, London E14 5AL.

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CALCULATION AGENCY AGREEMENT BETWEEN THERMO FISHER SCIENTIFIC (FINANCE I) B.V. AND THE BANK OF NEW YORK MELLON, LONDON BRANCH FLOATING RATE NOTES
Calculation Agency Agreement • August 8th, 2018 • Thermo Fisher Scientific Inc. • Measuring & controlling devices, nec • New York

THIS CALCULATION AGENCY AGREEMENT (this “Agreement”) is made as of August 8, 2018, between THERMO FISHER SCIENTIFIC (FINANCE I) B.V., a private company with limited liability (besloten vennootschap met beperkte aansprakelijkheid) incorporated under the laws of The Netherlands, with its corporate seat (statutaire zetel) at Breda, The Netherlands, and its registered office at Takkebijsters 1, 4817 BL Breda, The Netherlands, registered with the Dutch Trade Register of the Chamber of Commerce under number 66428319 (the “Company”), and THE BANK OF NEW YORK MELLON, LONDON BRANCH, as calculation agent (the “Calculation Agent”), whose principal executive office is located at One Canada Square, London E14 5AL.

THERMO FISHER SCIENTIFIC (FINANCE I) B.V., as Issuer THERMO FISHER SCIENTIFIC INC., as Guarantor AND THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., as Trustee SECOND SUPPLEMENTAL INDENTURE Dated as of August 8, 2018 Floating Rate Senior Notes due 2020
Supplemental Indenture • August 8th, 2018 • Thermo Fisher Scientific Inc. • Measuring & controlling devices, nec • New York

THIS SECOND SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”) is dated as of August 8, 2018 among THERMO FISHER SCIENTIFIC (FINANCE I) B.V., a private limited liability company (besloten vennootschap met beperkte aansprakelijkheid) incorporated under the laws of the Netherlands, with its corporate seat (statutaire zetel) in Breda, the Netherlands, and its registered office at Takkebijsters 1, 4817 BL Breda, the Netherlands, registered with the Dutch Trade Register of the Chamber of Commerce under number 66428319 (the “Company”), THERMO FISHER SCIENTIFIC INC., a Delaware corporation (the “Guarantor”), and THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., a national banking association, as trustee (the “Trustee”).

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