CRISPR THERAPEUTICS AG 4,210,526 Common Shares (nominal value CHF 0.03 per share) Underwriting AgreementCRISPR Therapeutics AG • September 21st, 2018 • Biological products, (no disgnostic substances) • New York
CRISPR Therapeutics AG, a stock corporation (Aktiengesellschaft) incorporated under the laws of Switzerland (the “Issuer”), proposes to sell to the several underwriters named in Schedule II hereto (the “Underwriters”), for whom you (the “Representatives”) are acting as representatives, 4,210,526 common shares, nominal value CHF 0.03 per share (“Common Shares”), of the Issuer (said shares to be issued and sold by the Issuer being hereinafter called the “Underwritten Securities”). The Issuer and the person named in Schedule III hereto (the “Selling Shareholder”) also propose to grant to the Underwriters an option to purchase up to the number of additional Common Shares set forth in Schedule I (the “Issuer Option Securities”) and Schedule III (the “Selling Shareholder Option Securities”), respectively (the Issuer Option Securities and the Selling Shareholder Option Securities, together, hereinafter called the “Option Securities;” the Option Securities, together with the Underwritten Secur
