0001193125-18-341227 Sample Contracts

Spero Therapeutics, Inc. Shares of Common Stock (par value $0.001 per share) Controlled Equity OfferingSM Sales Agreement
Spero Therapeutics, Inc. • December 3rd, 2018 • Pharmaceutical preparations • New York

Spero Therapeutics, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cantor Fitzgerald & Co. (the “Agent”), as follows:

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