0001193125-18-348868 Sample Contracts

ZYMEWORKS INC. as Issuer, as U.S. Trustee and as Canadian Trustee Indenture Dated as of
Zymeworks Inc. • December 13th, 2018 • Pharmaceutical preparations • Ontario

INDENTURE, dated as of , between ZYMEWORKS INC., a corporation duly continued and existing under the laws of British Columbia (herein called the “Company”), having its principal office at 1385 West 8th Avenue, Suite 540, Vancouver, British Columbia, V6H 3V9, and , a , organized under the laws of , as U.S. trustee (herein called the “U.S. Trustee”), and , as Canadian trustee (the “Canadian Trustee” and, together with the U.S. Trustee, the “Trustees”).

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